Does tadalafil increase PSA?

Changes in the total IPSS, IPSS irritative and obstructive subscores, IPSS health-related QoL and BII were maintained after 1 year and were similar despite the tadalafil dose administered during the double-blind study. During the open-label extension period, mean PSA increased from 1.6 ± 1.3 to 1.8 ± 1.4 ng/ml.

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