What is tadalafil half-life?

Duration of action The half-life of tadalafil is 17.5 hours in normal healthy men and 21.6 hours in elderly men, while the half-lives of sildenafil and vardenafil are similar at 4 hours (Francis and Corbin 2003). This longer half-life provides a therapeutic window of 36 hours for tadalafil (Porst et al 2003).

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